| DDSPC (CFSAN) | Division of Dietary Supplement Programs and Compliance (CFSAN) | |
| DDSPCM | Driver Door Switch Panel Control Module | |
| DDSR | Database Data Shape Resources | |
| DDSR | Debt and Debt Service Reduction | |
| DDSR | Downstate Delaware Striders Riders | |
| DDSR | Downstate Delaware Striders and Riders | |
| DDSRU | District Disease Surveillance and Response Units | |
| DDSRU | District Disease Surveillance Response Unit | |
| DDSRU | Disease Detection Surveillance and Response Unit | |
| DDSS | Double Dynamic Suspension System | |
| DDST | Denver Development Screening Test | |
| DDST | Denver Developmental Screening Test | |
| DDST | Drug Delivery Systems Technologies | |
| DDST | Double Disk Synergy Test | |
| DDST | Downsized Deployable Satellite Terminal | |
| DDST | Data Driven Self Timed | |
| DDST | Douglas Dolfins Swim Team | |
| DDST | Dothan Dolphin Swim Team | |
| DDST | Deputy Director for Science and Technology | |
| DDST | Division of Discovery Science Technology | |
| DDST | Double Daylight Saving Time | |
| DDST | Disaster Decision Support Tool | |
| DDST | Discovery and Delivery Study Team | |
| DDST | Deployment and Distribution Support Team | |
| DDST | Data Driven Smooth Tests |
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