| SIRB | Siriraj Institutional Review Board | |
| SIRB | Seton Institutional Review Board | |
| SIRB | Senior's Information & Resource Bureau | |
| SIRB | S Identification And Record Book | |
| SIRB | s Identification Record Book | |
| SIRB | System Implementation Review Board | |
| SIRB | Single Institutional Review Board | |
| SIRB | Seafarers Identification and Record Book | |
| SIRB | Single Institution Review Board | |
| SIRC | Sport Information Resource Centre | |
| SIRC | Social Issues Research Centre | |
| SIRC | Security Intelligence Review Committee | |
| SIRC | Spokane Intercollegiate Research Conference | |
| SIRC | Software Information Resource Corp | |
| SIRC | Strategic Infrastructure for Research Committee | |
| SIRC | Styrene Information Research Center | |
| SIRC | Simple Interface for Reconfigurable Computing | |
| SIRC | South Independent Rugby Conference | |
| SIRC | Science in the River City | |
| SIRC | Simulation Innovation Resource Center | |
| SIRC | Student and Industry Resource Center | |
| SIRC | Society for Implementation Research Collaboration | |
| SIRC | Southwest Interdisciplinary Research Center | |
| SIRC | Staten Island Railroad | |
| SIRC | Spinal Injury Rehabilitation Center |
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