| SPMS | Special Purpose Manipulator System | |
| SPMS | Sine Prole Mascila Superstite | |
| SPMS | Yurimaguas M.B. Rengifo, Peru | |
| SPMS | Secondary Progressive Multiple Sclerosis | |
| SPMS | Specialist Primary Medical Services | |
| SPMS | Specialist Provider Medical Services | |
| SPMS | School of Physical and Mathematical Sciences | |
| SPMS | Severna Park Middle School | |
| SPMS | Surplus Property Management System | |
| SPMS | Starting Position of miRNA Seed | |
| SPMS | Scientific Programme Management System | |
| SPMS | South Plainfield Middle School | |
| SPMS | Scanning probe microscopy SPM | |
| SPMS | Switzerland Point Middle School | |
| SPMS | South Pasadena Middle School | |
| SPMS | Stuart Pepper Middle School | |
| SPMS | Summit Parkway Middle School | |
| SPMS | South Park Middle School | |
| SPMS | South Park Middle School | |
| SPMS | St Pauls Middle School | |
| SPMS | Simple Project Management System | |
| SPMS | Sage Park Middle School | |
| SPMS | Sage Park Middle School | |
| SPMS | Southern Pacific Masters Swimming | |
| SPMS | Structured Patterns Metamodel Standard |
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