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What does CADASIL stand for? 

What does CADASIL mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: CADASIL.

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CADASIL

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

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What does CADASIL mean?

CADASIL
CADASIL or CADASIL syndrome, involving cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy, is the most common form of hereditary stroke disorder, and is thought to be caused by mutations of the Notch 3 gene on chromosome 19. The disease belongs to a family of disorders called the leukodystrophies. The most common clinical manifestations are migraine headaches and transient ischemic attacks or strokes, which usually occur between 40 and 50 years of age, although MRI is able to detect signs of the disease years prior to clinical manifestation of disease.The condition was identified and named by French researchers Marie-Germaine Bousser and Elisabeth Tournier-Lasserve in the 1990s. Together with two other researchers, Hugues Chabriat and Anne Joutel, they received the 2019 Brain Prize for their research into the condition.

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    A To Be Adored
    B To Be Arranged
    C To Be Applied
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