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What does DICKKOPF stand for? 

What does DICKKOPF mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: DICKKOPF.

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Dickkopf

Dickköpfe

International » German

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Dickkopf

Dickkopffalter

International » German

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What does DICKKOPF mean?

Dickkopf
Dickkopf (DKK) is a family of proteins consisting of five members as of 2020. The most well-studied is Dickkopf-related protein 1 (DKK1). DKK proteins inhibit the Wnt signaling pathway coreceptors LRP5 and LRP6. They bind with high affinity as ligands to KREMEN1 and KREMEN2, which are transmembrane proteins. DKK proteins have important roles in the development of vertebrates.

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