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What does RITS mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: RITS.

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RITS

Rock Island Technical Society

Miscellaneous » Hobbies

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Rhode Island Training School

Community » Schools

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RITS

Radiatively Important Trace Species

Academic & Science » Ocean Science

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RITS

Remediation Innovative Technology Seminar

Governmental » Environmental -- and more...

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Residential Information Technology Services

Computing » Telecom

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RITS

Racing In The Rockies

Sports » Racing

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RITS

Rotary International Travel Services

Community » Travel & Tourism

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RNA induced transcriptional silencing

Miscellaneous » Unclassified

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RITS

Royal Institute of Technology and Science

Computing » Technology

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RITS

Record Integration Tracking System

Miscellaneous » Unclassified

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RITS

Relationship Information Tracking System

Miscellaneous » Unclassified

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RITS

Research Information Technology Systems

Computing » Technology

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RITS

Retailer Inventory Tracking System

Miscellaneous » Unclassified

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RITS

Racing In The Street

Miscellaneous » Automotive

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RITS

Raised In The South

Miscellaneous » Funnies

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What does RITS mean?

rits
RNA-induced transcriptional silencing (RITS) is a form of RNA interference by which short RNA molecules – such as small interfering RNA (siRNA) – trigger the downregulation of transcription of a particular gene or genomic region. This is usually accomplished by posttranslational modification of histone tails (e.g. methylation of lysine 9 of histone H3) which target the genomic region for heterochromatin formation. The protein complex that binds to siRNAs and interacts with the methylated lysine 9 residue of histones H3 is the RITS complex. RITS was discovered in the fission yeast Schizosaccharomyces pombe, and has been shown to be involved in the initiation and spreading of heterochromatin in the mating-type region and in centromere formation. The RITS complex in S. pombe contains at least a piwi domain-containing RNase H-like argonaute, a chromodomain protein Chp1, and an argonaute interacting protein Tas3 which can also bind to Chp1, while heterochromatin formation has been shown to require at least argonaute and an RNA-dependent RNA polymerase. Loss of these genes in S. pombe results in abnormal heterochromatin organization and impairment of centromere function, resulting in lagging chromosomes on anaphase during cell division.

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