We've got 4 definitions »

What does SPEN stand for? 

What does SPEN mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: SPEN.

Filter by: Sort by:PopularityAlphabeticallyCategory

Sports Entertainment Enterprises

Business » NASDAQ Symbols

Rate it:

Special Program for Elementary Needs

Miscellaneous » Unclassified

Rate it:

Iscozacin, Peru

Regional » Airport Codes

Rate it:

Serial Peripheral Enable

Computing » IT

Rate it:

What does SPEN mean?

Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.

see more »

Discuss these SPEN abbreviations with the community:


    Know what is SPEN? Got another good explanation for SPEN? Don't keep it to yourself!

    Still can't find the acronym definition you were looking for? Use our Power Search technology to look for more unique definitions from across the web!


    Use the citation options below to add these abbreviations to your bibliography.


    "SPEN." Abbreviations.com. STANDS4 LLC, 2023. Web. 28 May 2023. <https://www.abbreviations.com/SPEN>.

    Browse Abbreviations.com

    Free, no signup required:

    Add to Chrome

    Get instant explanation for any acronym or abbreviation that hits you anywhere on the web!

    Free, no signup required:

    Add to Firefox

    Get instant explanation for any acronym or abbreviation that hits you anywhere on the web!


    The ultimate acronym test

    • A. Feel Magnificent
    • B. Frequency Moderator
    • C. Frequency Modulation
    • D. Fly Morroco


    Share an image of SPEN


    Hearing impaired tip:

    Sign language

    How do you say SPEN in ASL sign language fingerspelling?