| SIGA | Siga Technologies, Inc. | |
| SIGA | Southern Indiana Gamers Association | |
| SigA | secretory immunoglobulin A | |
| SIGA | Southern Illinois Golf Association | |
| SIGA | Sistema Integrado Guatemalteco de Autobuses | |
| SIGA | Saskatchewan Indian Gaming Authority | |
| SIGA | Sunshine in Government Act | |
| SIGA | Salesian Institute of Graphic Arts | |
| SIGA | Secure Internet Gateway Appliance | |
| SIGA | Sport Integrity Global Alliance | |
| SIGA | Sport Integrity Global Alliance | |
| SIGA | SSEAYP International General Assembly | |
| SIGA | SSEAYP International General Assembly | |
| SIGABRT | SIGnal: ABoRT | |
| SIGACT | Special Interest Group on Algorithms and Computation Theory | |
| SIGACTS | significant activities | |
| SIGADA | Special Interest Group for ADA | |
| SIGAGF! | Sometimes I Get A Good Feeling!(Avicii - Levels) | |
| SIGALRM | SIGnal: ALaRM clock | |
| SIGALRM | SIGnal ALaRM | |
| SIGAM | Special Interest Group in Amputee Medicine | |
| SIGAM | Special Interest Group for Amputee Medicine | |
| SIGAP | SIstema de Areas Protegidas de Guatemala | |
| SIGBUS | SIGnal: BUS error | |
| SIGC | Symons International Group, Inc. |
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