What does ISA stand for? 

ISA

ISA is an initialism for International Security Alliance, a fictional intelligence agency on the soap opera Days of our Lives. A highly secretive organization, its agents have been operating in the small Midwestern town of Salem at least since its first appearance on the show in the early 1980s. It is the counterpart to a similar organization on rival soap General Hospital, the WSB, which appeared on that show around the same time. The ISA is a sort of combination of a law enforcement organization, such as the FBI, DEA, or Interpol, and a spy agency, such as the CIA or Britain's MI-6. Indeed, several of the agents on the show have been British, especially in the 1980s, although the agency's main headquarters have always been purported to be in Washington, DC, and in more recent years the agency has in fact been identified more specifically as a branch of the U.S. government. The agency's mandate does appear to be more centered on law enforcement, with a specialty in the sort of high-level, international organized crime that has tended to center in the otherwise quiet town of Salem.

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