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What does RITS stand for?
What does RITS mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: RITS.
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Term | Definition | Rating |
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RITS | Rock Island Technical Society | |
RITS | Rhode Island Training School | |
RITS | Radiatively Important Trace Species | |
RITS | Remediation Innovative Technology Seminar | |
RITS | Residential Information Technology Services | |
RITS | Racing In The Rockies | |
RITS | Rotary International Travel Services | |
RITS | RNA induced transcriptional silencing | |
RITS | Royal Institute of Technology and Science | |
RITS | Record Integration Tracking System | |
RITS | Relationship Information Tracking System | |
RITS | Research Information Technology Systems | |
RITS | Retailer Inventory Tracking System | |
RITS | Racing In The Street | |
RITS | Raised In The South |
What does RITS mean?
- rits
- RNA-induced transcriptional silencing (RITS) is a form of RNA interference by which short RNA molecules – such as small interfering RNA (siRNA) – trigger the downregulation of transcription of a particular gene or genomic region. This is usually accomplished by posttranslational modification of histone tails (e.g. methylation of lysine 9 of histone H3) which target the genomic region for heterochromatin formation. The protein complex that binds to siRNAs and interacts with the methylated lysine 9 residue of histones H3 is the RITS complex. RITS was discovered in the fission yeast Schizosaccharomyces pombe, and has been shown to be involved in the initiation and spreading of heterochromatin in the mating-type region and in centromere formation. The RITS complex in S. pombe contains at least a piwi domain-containing RNase H-like argonaute, a chromodomain protein Chp1, and an argonaute interacting protein Tas3 which can also bind to Chp1, while heterochromatin formation has been shown to require at least argonaute and an RNA-dependent RNA polymerase. Loss of these genes in S. pombe results in abnormal heterochromatin organization and impairment of centromere function, resulting in lagging chromosomes on anaphase during cell division.
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